Relationship between alcoholism and CYP2E1 C/D polymorphism.

doi:10.1159/000026544

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Article

Relationship between alcoholism and CYP2E1 C/D polymorphism.

Neuropsychobiology - 1 Nov 1998

Iwahashi K, Ameno S, Ameno K, Okada N, Kinoshita H, Sakae Y, Nakamura K, Watanabe M, Ijiri I, Harada S

Abstract excerpt

The genotypes of the CYP2E1 loci of 35 alcoholic and 130 nonalcoholic (healthy controls) Japanese were investigated to determine the relationship between CYP2E1 (C/D) polymorphism and susceptibility to alcohol dependence. There was a significant (d.f. = 1, chi2 = 11.0, p < 0.001) difference in th...

Topics

Adult
Alcoholism
Alleles
Cytochrome P-450 CYP2E1
Gene Frequency
Genotype
Humans
Japan
Male
Polymorphism, Genetic

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