[Replicative properties of HIV-1 strains, resistant to 3'-azido-2'3'-dideoxythymidine].

Article

[Replicative properties of HIV-1 strains, resistant to 3'-azido-2'3'-dideoxythymidine].

Voprosy virusologii - 1 Jan 2000

Selimova L M, Iurin O G, Pokrovskiĭ V V

Abstract excerpt

The replicative activity of two strains of human immunodeficiency virus type I, 1974 and 1978, resistant to 3'-azido-2',3'-dideoxythymidine (AZT), was investigated. Assessment of AZT sensitivity by the standard method showed the 50% effective dose (ED50) for strain 1974 to be 0.1 mumole and for s...

Topics

Cell Survival
Drug Resistance, Microbial
HIV-1
Humans
Jurkat Cells
Microbial Sensitivity Tests
Phenotype
Species Specificity
Virus Replication
Zidovudine

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.