Article
Inhibition by AZT of HIV-1 replication in acutely infected U-937 cells.
Journal of leukocyte biology - 1 Jun 1990
Boulerice F, Wainberg M A
Abstract excerpt
We studied the effect of AZT on the replication of HIV-1 in freshly and chronically infected U-937 monocytoid cells over a period of 2 months. Expression of viral antigens was monitored by indirect immunofluorescence, and viral replication was assessed by reverse transcriptase assay on virus pell...
Topics
- Dose-Response Relationship, Drug
- Drug Resistance, Microbial
- Gene Expression Regulation, Viral
- Genetic Variation
- HIV-1
- Humans
- Hydrocortisone
- Lymphoma, Large B-Cell, Diffuse
- Tumor Cells, Cultured
- Virus Replication
- Zidovudine
