Article
Inhibition by AZT of HIV-1 replication in acutely infected U-937 cells.
Journal of leukocyte biology - 1 Jun 1990
Boulerice F, Wainberg M A
Abstract excerpt
We studied the effect of AZT on the replication of HIV-1 in freshly and chronically infected U-937 monocytoid cells over a period of 2 months. Expression of viral antigens was monitored by indirect immunofluorescence, and viral replication was assessed by reverse transcriptase assay on virus pelleted from culture fluids. In U-937 cells not treated by AZT, viral antigens were expressed by 7 days after infection....
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