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Article

Identification of a profilin homologue in Trypanosoma brucei by complementation screening.

Gene - 18 Mar 1997

Wilson W, Seebeck T

Abstract excerpt

Using genetic complementation in Saccharomyces cerevisiae, we have isolated a Trypanosoma brucei gene encoding profilin. Overexpression of trypanosome profilin suppresses defects that are associated with the loss of the C-terminal domain of the adenylyl cyclase-associated protein in S. cerevisiae. Similarly, the T. brucei gene complements a profilin-deletion mutant of S. cerevisiae. The full-length cDNA clone...

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PMID: 9099881
DOI: 10.1016/s0378-1119(96)00749-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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