Article
Cloning and characterization of the phosphoglucomutase of Trypanosoma cruzi and functional complementation of a Saccharomyces cerevisiae PGM null mutant.
Glycobiology - 1 Dec 2005
Penha Luciana L, Mendonça-Previato Lucia, Previato Jose O, Scharfstein Julio, Heise Norton, Lima Ana Paula C de A
Abstract excerpt
Trypanosoma cruzi is the etiological agent of Chagas' disease, a chronic illness characterized by progressive cardiomyopathy and/or denervation of the digestive tract. The parasite surface is covered with glycoconjugates, such as mucin-type glycoproteins and glycoinositolphospholipids (GIPLs), whose glycans are rich in galactopyranose (Galp) and/or galactofuranose (Galf) residues. These molecules have been...
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