Article
Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei.
The Journal of biological chemistry - 8 Oct 2004
Uzcategui Nestor L, Szallies Alexander, Pavlovic-Djuranovic Slavica, Palmada Monica, Figarella Katherine, Boehmer Christoph, Lang Florian, Beitz Eric, Duszenko Michael
Abstract excerpt
Trypanosoma brucei, causative for African sleeping sickness, relies exclusively on glycolysis for ATP production. Under anaerobic conditions, glucose is converted to equimolar amounts of glycerol and pyruvate, which are both secreted from the parasite. As we have shown previously, glycerol transport in T. brucei occurs via specific membrane proteins (Wille, U., Schade, B., and Duszenko, M. (1998) Eur. J. Biochem....
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