Article
Hypoallergenic profilin--a new way to identify allergenic determinants.
The FEBS journal - 1 Aug 2012
Paulus Kathrin E, Schmid Benedikt, Zajic Doreen, Schäfer Alice, Mahler Vera, Sonnewald Uwe
Abstract excerpt
Plant profilins are important panallergens, contributing to numerous food and pollen allergies. They fulfil essential functions in all eukaryotic cells, including yeast and mammals, making breeding of profilin-deficient crop plants an impossible task. To obtain hypoallergenic profilin-variants, a novel yeast based screening system to select for fully active but hypoallergenic profilins was developed. Despite...
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