Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of yeast profilin.

Molecular and cellular biology - 1 Dec 1993

Haarer B K, Petzold A S, Brown S S

Abstract excerpt

We have mutated two regions within the yeast profilin gene in an effort to functionally dissect the roles of actin and phosphatidylinositol 4,5-bisphosphate (PIP2) binding in profilin function. A series of truncations was carried out at the C terminus of profilin, a region that has been implicate...

Topics

Acanthamoeba
Actins
Amino Acid Sequence
Animals
Base Sequence
Contractile Proteins
DNA Mutational Analysis
DNA, Fungal
Gene Expression
Genes, Fungal
Genes, Protozoan
Microfilament Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phosphatidylinositol 4,5-Diphosphate

Phosphatidylinositol Phosphates

Profilins

Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8247001
DOI: 10.1128/mcb.13.12.7864-7873.1993
PMCID: PMC364858

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8247001-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of yeast profilin.PMID 8247001Read ↗

Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells.Semantic proximity Read ↗

Structure and function of profilin.Semantic proximity Read ↗

Profilin binding to poly-L-proline and actin monomers along with ability to catalyze actin nucleotide exchange is required for viability of fission yeast.Semantic proximity Read ↗

Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12.Semantic proximity Read ↗

Mechanism and biological role of profilin-Srv2/CAP interaction.Semantic proximity Read ↗

Suppression of the profilin-deficient phenotype by the RHO2 signaling pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Rapid screening for temperature-sensitive alleles in plants.Semantic proximity Read ↗

Genetic suppression of defective profilin by attenuated Myosin II reveals a potential role for Myosin II in actin dynamics in vivo in fission yeast.Semantic proximity Read ↗

Profilin mutations disrupt multiple actin-dependent processes during Drosophila development.Semantic proximity Read ↗

The characterization of ligand-specific maize (Zea mays) profilin mutants.Semantic proximity Read ↗

Identification of a suppressor of the Dictyostelium profilin-minus phenotype as a CD36/LIMP-II homologue.Semantic proximity Read ↗

Hypoallergenic profilin--a new way to identify allergenic determinants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.