Article
DUAL ROLE OF MANNAN‐BINDING PROTEIN IN INFECTIONS: ANOTHER CASE OF HETEROSIS?
1 Apr 1994
Abstract excerpt
Human mannan-binding protein (MBP) is a serum lectin that participates in the immune defence by mediating phagocytosis and activation of complement. Variant MBP alleles causing dominant low-serum concentrations have high frequencies in all populations studied, and therefore, low MBP concentrations may confer selective advantages to those individuals carrying the variant alleles. Mycobacterium leprae, the...
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