Article
Interruption of the phosphoglucose isomerase gene results in glucose auxotrophy in Mycobacterium smegmatis.
Journal of bacteriology - 1 Apr 1997
Tuckman D, Donnelly R J, Zhao F X, Jacobs W R, Connell N D
Abstract excerpt
Two glycerol utilization mutants of Mycobacterium smegmatis that were unable to utilize most carbon sources except glucose were isolated. Supplementation of these media with small amounts of glucose restored growth in the mutants; these strains are therefore glucose auxotrophs. The mutant phenotype is complemented by the gene encoding phosphoglucose isomerase (pgi), and direct measurement of enzyme activities in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
