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Article

Glucose 6-phosphate accumulation in mycobacteria: implications for a novel F420-dependent anti-oxidant defense system.

The Journal of biological chemistry - 18 Jun 2010

Hasan Mohammad Rubayet, Rahman Mahbuba, Jaques Sandford, Purwantini Endang, Daniels Lacy

Abstract excerpt

Glucose 6-phosphate (G6P) is a metabolic intermediate with many possible cellular fates. In mycobacteria, G6P is a substrate for an enzyme, F(420)-dependent glucose-6-phosphate dehydrogenase (Fgd), found in few bacterial genera. Intracellular G6P levels in six Mycobacterium sp. were remarkably higher ( approximately 17-130-fold) than Escherichia coli and Bacillus megaterium. The high G6P level in Mycobacterium...

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Identifiers

PMID: 20075070
DOI: 10.1074/jbc.M109.074310
PMCID: PMC2885192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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