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Identification of a Novel Gene Product That Promotes Survival of Mycobacterium smegmatis in Macrophages

21 Feb 2012

Abstract excerpt

BACKGROUND: Bacteria of the suborder Corynebacterineae include significant human pathogens such as Mycobacterium tuberculosis and M. leprae. Drug resistance in mycobacteria is increasingly common making identification of new antimicrobials a priority. Mycobacteria replicate intracellularly, most commonly within the phagosomes of macrophages, and bacterial proteins essential for intracellular survival and...

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PMID: 22363734
DOI: 10.1371/journal.pone.0031788

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