Article
Identification of a novel protein with a role in lipoarabinomannan biosynthesis in mycobacteria.
The Journal of biological chemistry - 7 Apr 2006
Kovacevic Svetozar, Anderson Dianne, Morita Yasu S, Patterson John, Haites Ruth, McMillan Benjamin N I, Coppel Ross, McConville Malcolm J, Billman-Jacobe Helen
Abstract excerpt
All species of Mycobacteria synthesize distinctive cell walls that are rich in phosphatidylinositol mannosides (PIMs), lipomannan (LM), and lipoarabinomannan (LAM). PIM glycolipids, having 2-4 mannose residues, can either be channeled into polar PIM species (with 6 Man residues) or hypermannosylated to form LM and LAM. In this study, we have identified a Mycobacterium smegmatis gene, termed lpqW, that is required...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
