Article
Inactivation of MSMEG_0412 gene drastically affects surface related properties of Mycobacterium smegmatis.
BMC microbiology - 8 Nov 2016
Zanfardino Anna, Migliardi Adriana, D'Alonzo Daniele, Lombardi Angela, Varcamonti Mario, Cordone Angela
Abstract excerpt
BACKGROUND: The outermost layer of mycobacterial cell wall is rich in lipids and glycolipids, surface molecules which differ among species. Mycobacterium smegmatis, an attractive model for the study of both pathogenic and non-pathogenic mycobacteria, presents glycopeptidolipids (GPLs). All the genes necessary for the biosynthesis of such molecules are clustered in a single region of 65 kb and among them, the...
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