Article
Deletion of PimE mannosyltransferase results in increased copper sensitivity in Mycobacterium smegmatis.
FEMS microbiology letters - 1 Mar 2018
Eagen William J, Baumoel Lisa R, Osman Sarah H, Rahlwes Kathryn C, Morita Yasu S
Abstract excerpt
The unique cell envelope structure of Mycobacterium tuberculosis is fundamental to its pathogenesis. Phosphatidylinositol (PI)-anchored glycolipids, such as phosphatidylinositol mannosides (PIMs), lipomannan and lipoarabinomannan, are essential components of the cell envelope widely conserved among mycobacteria, but their roles in the cell envelope integrity are not fully understood. We previously identified PimE...
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