Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function.

The Journal of biological chemistry - 22 Oct 2004

Johnson Daniel, Montpetit Marty L, Stocker Patrick J, Bennett Eric S

Abstract excerpt

Voltage-gated sodium channels (Nav) are responsible for initiation and propagation of nerve, skeletal muscle, and cardiac action potentials. Nav are composed of a pore-forming alpha subunit and often one to several modulating beta subunits. Previous work showed that terminal sialic acid residues...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbohydrates
Share to Electrophysiology
Share to Glycosylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Potentials

Share to N-Acetylneuraminic Acid

Share to Sialic Acids

Share to Sodium

Share to Sodium Channels

Source

Identifiers

PMID: 15316006
DOI: 10.1074/jbc.M408900200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15316006-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function.PMID 15316006Read ↗

Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function.Semantic proximity Read ↗

Contribution of sialic acid to the voltage dependence of sodium channel gating. A possible electrostatic mechanism.Semantic proximity Read ↗

Alterations of the Sialylation Machinery in Brugada Syndrome.Semantic proximity Read ↗

The extracellular domain of the beta1 subunit is both necessary and sufficient for beta1-like modulation of sodium channel gating.Semantic proximity Read ↗

Voltage-Gated Sodium Channel β Subunits and Their Related Diseases.Semantic proximity Read ↗

The molecular mechanism of sialic acid transport mediated by Sialin.Semantic proximity Read ↗

Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels.Semantic proximity Read ↗

Structural basis for the delivery of activated sialic acid into Golgi for sialyationSemantic proximity Read ↗

Effects of Kv1.1 channel glycosylation on C-type inactivation and simulated action potentials.Semantic proximity Read ↗

Nav1.5 channels can reach the plasma membrane through distinct N-glycosylation states.Semantic proximity Read ↗

N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling.Semantic proximity Read ↗

Functional characterization of vesicular excitatory amino acid transport by human sialin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.