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Article

Pathobiology of aging mice and GEM: background strains and experimental design.

Veterinary pathology - 1 Jan 2012

Brayton C F, Treuting P M, Ward J M

Abstract excerpt

The use of induced and spontaneous mutant mice and genetically engineered mice (and combinations thereof) to study cancers and other aging phenotypes to advance improved functional human life spans will involve studies of aging mice. Genetic background contributes to pathology phenotypes and to causes of death as well as to longevity. Increased recognition of expected phenotypes, experimental variables that...

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Source

Identifiers

PMID: 22215684
DOI: 10.1177/0300985811430696

Genes

GEM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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