Article
Mouse and rat genotype choices.
Experimental gerontology - 1 Jan 2000
Sprott R L
Abstract excerpt
There are advantages and disadvantages to all animal models for aging research. Investigators need to understand these issues, as well as the nature of each relevant model, to choose the best model for their research. There is no, "best" or "worst" model for aging research. Five genetically defined rodent models of potential utility in aging research are: (1) inbred strains and F1 hybrid mice and rats, (2) single...
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