Article
Expression of mdr1 and mrp in the normal B-cell homologue of B-cell chronic lymphocytic leukaemia.
British journal of haematology - 1 Mar 1997
Wall D M, el-Osta S, Tzelepis D, Bertoncello I, Kantharidis P, Chou S T, Zalcberg J R, Parkin J D
Abstract excerpt
B-cell chronic lymphocytic leukaemia (CLL) cells commonly express the multidrug resistance phenotype. The aim of this study was to establish whether the normal homologue in B-cell ontogeny of B-CLL also expressed the multidrug resistance (mdr) phenotype. Human tonsillar lymphocytes were sorted to yield two B-cell subsets based on the expression of CD19, CD5 and CD10. The normal homologue was represented by a...
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