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Article

Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype.

Blood - 1 Dec 1992

Drach D, Zhao S, Drach J, Mahadevia R, Gattringer C, Huber H, Andreeff M

Abstract excerpt

The multidrug-resistance gene, MDR1 is expressed in many normal tissues, but little is known about its expression in normal hematopoietic cells. Using the monoclonal antibody C219 and flow cytometric analysis, P-glycoprotein (P-gp) was found to be expressed in all peripheral blood (PB) subpopulations (CD4, CD8, CD14, CD19, CD56) except granulocytes. To specifically determine MDR1 gene expression, these PB...

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PMID: 1360266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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