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Article

Renal hemodynamic changes induced by captopril and angiotensin-converting enzyme gene polymorphism.

Nephron - 1 Jan 1997

Mizuiri S, Hemmi H, Inoue A, Takano M, Kadomatsu S, Tanimoto H, Tanegashima M, Hayashi I, Fushimi T, Hasegawa A

Abstract excerpt

We studied the relationship between renal hemodynamic changes induced by a single acute administration of captopril (50 mg p.o.) and angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism in 27 healthy human volunteers, 7 with DD genotype, 10 with ID, and 10 with II genotype. The increase in effective renal plasma flow (p < 0.02) and the fall in renal vascular resistance (p < 0.01) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9069453
DOI: 10.1159/000189554

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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