Article
Modulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients.
Diabetes - 1 Oct 2005
Weekers Laurent, Bouhanick Béatrice, Hadjadj Samy, Gallois Yves, Roussel Ronen, Pean Franck, Ankotche Amos, Chatellier Gilles, Alhenc-Gelas François, Lefebvre Pierre J, Marre Michel
Abstract excerpt
ACE inhibition protects kidney function, but ACE insertion/deletion (I/D) polymorphism affects renal prognosis in type 1 diabetic patients. ACE genotype may influence the renal benefits of ACE inhibition. We studied the impact of ACE I/D polymorphism on the renal hemodynamic changes induced by ACE inhibition in type 1 diabetes. We studied renal hemodynamics (glomerular filtration rate [GFR], effective renal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.