Angiotensin converting enzyme gene polymorphism and renal hemodynamic function in early diabetes.

doi:10.1038/ki.1997.15

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Article

Angiotensin converting enzyme gene polymorphism and renal hemodynamic function in early diabetes.

Kidney international - 1 Jan 1997

Miller J A, Scholey J W, Thai K, Pei Y P

Abstract excerpt

An insertion/deletion (I/D) of the human angiotensin converting enzyme (ACE) gene is a major determinant of circulating ACE levels. Recent studies suggest that the ACE I/D polymorphism may influence the risk of developing nephropathy in patients with insulin dependent diabetes mellitus (IDDM), al...

Topics

Adult
Diabetes Mellitus, Type 1
Diabetic Nephropathies
Female
Gene Expression Regulation, Enzymologic
Genotype
Glomerular Filtration Rate
Humans
Inulin
Kidney
Male
Peptidyl-Dipeptidase A
Polymerase Chain Reaction
Polymorphism, Genetic
Renal Circulation
p-Aminohippuric Acid

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Open in PubMed

Identifiers

PMID: 8995725
DOI: 10.1038/ki.1997.15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8995725-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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