Article
Involvement of renin-angiotensin system in pressure-flow relationship: role of angiotensin-converting enzyme gene polymorphism.
Anesthesiology - 1 Feb 2002
Lasocki Sigismond, Iglarz Marc, Seince Pierre-François, Vuillaumier-Barrot Sandrine, Vicaut Eric, Henrion Daniel, Levy Bernard, Desmonts Jean-Marie, Philip Ivan, Bénessiano Joelle
Abstract excerpt
BACKGROUND: The renin-angiotensin system is involved in blood pressure regulation. The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is known to be associated with variation of plasma and cellular ACE concentrations. Furthermore, changes in arterial function have been suggested to be associated to the DD genotype. The aim of the study was to investigate the arterial...
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