Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic basis of pituitary adenoma invasiveness: a review.

Journal of neuro-oncology - 1 May 2001

Suhardja A, Kovacs K, Rutka J

Abstract excerpt

Compatible with contemporary paradigms of the role of genetic aberrations in the progression of human tumors, the growth of pituitary tumors into a state of invasiveness appears to be due to genetic alterations. Amplification of H-ras and c-myc oncogenes and mutations of p53, nm23 and Rb genes have been identified disproportionately more in aggressive tumors and, in the case of Rb gene, in pituitary carcinomas,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, myc
Share to Genes, Retinoblastoma
Share to Monomeric GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to NM23 Nucleoside Diphosphate Kinases

Share to Nucleoside-Diphosphate Kinase

Share to Pituitary Neoplasms

Share to Proto-Oncogene Proteins c-myc

Share to Retinoblastoma Protein

Source

Identifiers

PMID: 11519849
DOI: 10.1023/a:1010655419332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic basis of pituitary adenoma invasiveness: a review.PMID 11519849Read ↗

Aggressive Pituitary TumorsSemantic proximity Read ↗

Pituitary adenoma pathogenesis: an update.Semantic proximity Read ↗

Pathogenesis of pituitary tumors.Semantic proximity Read ↗

Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors.Semantic proximity Read ↗

[Update on mechanisms of pituitary tumorigenesis.]Semantic proximity Read ↗

Advances in pathogenesis of pituitary adenomas.Semantic proximity Read ↗

Molecular pathogenesis of pituitary tumors.Semantic proximity Read ↗

[Pituitary adenoma: mechanisms of endocrine oncogenesis].Semantic proximity Read ↗

Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker.Semantic proximity Read ↗

Molecular basis of pituitary oncogenesis.Semantic proximity Read ↗

[Pituitary adenomas: a pathway to understanding the aggressive form. Clinical genetic analysis of potential prognostic markers in the development of aggressive pituitary adenomas].Semantic proximity Read ↗

ras mutations in human prolactinomas and pituitary carcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.