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Article

Genome-wide amplification and allelotyping of sporadic pituitary adenomas identify novel regions of genetic loss.

Genes, chromosomes & cancer - 1 Jul 2003

Simpson D J, Bicknell E J, Buch H N, Cutty S J, Clayton R N, Farrell W E

Abstract excerpt

Through the use of a candidate gene approach, several previous studies have identified loss of heterozygosity (LOH) at putative tumor-suppressor gene (TSG) loci in sporadic pituitary tumors. This study reports a genome-wide allelotyping by use of 122 microsatellite markers in a large cohort of tumors, consisting of somatotrophinomas and non-functioning adenomas. Samples were first subject to prior whole genome...

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Identifiers

PMID: 12759921
DOI: 10.1002/gcc.10216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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