Article
Expression of exogenous NF-IL6 induces apoptosis in Sp2/0-Ag14 myeloma cells.
DNA and cell biology - 1 Feb 1997
Zhu M S, Liu D G, Cheng H Q, Xu X Y, Li Z P
Abstract excerpt
NF-IL6 (or C/EBP beta) is a multifunctional transcription factor of the C/EBP family. To study the effects of exogenous expression of NF-IL6 on the growth of cells of hematopoietic tumors, we infected SP2/0-Ag14 myeloma cells with pLXSN recombinant retrovirus harboring the NF-IL6 cDNA. We found that the transfected cells revealed changes typical of the apoptosis and finally died. The expression of NF-IL6 protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
