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Article

A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells

15 May 2003

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Share to Cell death mechanisms and regulation
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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12771946
DOI: 10.1038/sj.onc.1206423

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Related research

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A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cellsPMID 12771946Read ↗

Mcl‐1 and Bcl‐x<sub>L </sub> are co‐regulated by IL‐6 in human myeloma cellsSemantic proximity Read ↗

Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation.Semantic proximity Read ↗

The imbalance between Bim and Mcl‐1 expression controls the survival of human myeloma cellsSemantic proximity Read ↗

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Expression of the bcl‐2 family of pro‐ and anti‐apoptotic genes in multiple myeloma and normal plasma cellsSemantic proximity Read ↗

Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1Semantic proximity Read ↗

Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis.Semantic proximity Read ↗

Mcl-1 as a therapeutic target in acute myelogenous leukemia (AML)Semantic proximity Read ↗

Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway.Semantic proximity Read ↗

Activating mutations in STAT3 and STAT5 differentially affect cellular proliferation and apoptotic resistance in multiple myeloma cells.Semantic proximity Read ↗

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptorSemantic proximity Read ↗

The antiapoptotic member of the Bcl-2 family Mcl-1 is a CTL target in cancer patientsSemantic proximity Read ↗

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