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Article

Induction of human cytotoxic T lymphocytes specific for prostate-specific antigen

1 Feb 1997

Abstract excerpt

Prostate-specific antigen (PSA), a tissue-specific protein expressed by most adenocarcinomas of the prostate, might be a useful target for T-cell-mediated immunotherapy of prostate cancers. The current study examined whether it is possible to elicit human cytotoxic T lymphocytes (CTL) with specificity for PSA. A synthetic nonamer peptide, corresponding to residues 146-154 of PSA and containing a canonical...

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PMID: 9051144
DOI: 10.1002/(sici)1097-0045(19970201)30:2<73::aid-pros1>3.0.co;2-l

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