Article
In vitro induction of HLA-A2402-restricted and carcinoembryonic-antigen-specific cytotoxic T lymphocytes on fixed autologous peripheral blood cells.
Cancer immunology, immunotherapy : CII - 1 Oct 1998
Kim C, Matsumura M, Saijo K, Ohno T
Abstract excerpt
HLA-A2402-restricted and carcinoembryonic-antigen(CEA)-specific cytotoxic T lymphocytes (CTL) were induced by culturing human peripheral blood mononuclear cells (PBMC) on formalin-fixed autologous adhesive PBMC that had been loaded with CEA-bound latex beads. The CTL killed the CEA-producing HLA-...
Topics
- Adenocarcinoma
- Antigens, Neoplasm
- Carcinoembryonic Antigen
- Cell Adhesion
- Cell Division
- Cells, Cultured
- Colonic Neoplasms
- Epitopes
- HLA-A Antigens
- Humans
- Kidney Neoplasms
- Leukocytes, Mononuclear
- Lymphocyte Activation
- Macrophages
- Peptide Fragments
- Phenotype
- Stomach Neoplasms
- T-Lymphocytes, Cytotoxic