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Article

Substitution analog peptide derived from HER-2 can efficiently induce HER-2-specific, HLA-A24 restricted CTLs.

Cancer immunology, immunotherapy : CII - 1 Nov 2006

Mimura Kousaku, Kono Koji, Southwood Scott, Fikes John, Takahashi Akihiro, Miyagawa Naoto, Sugai Hidemitsu, Fujii Hideki

Abstract excerpt

In order to broaden the possibility for anti-HER-2/neu (HER-2) immune targeting, it is important to identify HLA-A24 restricted peptide epitopes derived from HER-2, since HLA-A24 is one of the most common alleles in Japanese and Asian people. In the present study, we have screened HER-2-derived,...

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Topics

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Share to Antigens, Neoplasm
Share to Cytotoxicity, Immunologic
Share to Epitopes, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-A Antigens

Share to HLA-A24 Antigen

Share to Inhibitory Concentration 50

Share to Receptor, ErbB-2

Share to T-Lymphocytes, Cytotoxic

Source

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Identifiers

PMID: 16435129
DOI: 10.1007/s00262-006-0123-0
PMCID: PMC11030792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16435129-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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