Article
Laryngeal and oropharyngeal cancer, and alcohol dehydrogenase 3 and glutathione S-transferase M1 polymorphisms.
Human genetics - 1 Mar 1997
Coutelle C, Ward P J, Fleury B, Quattrocchi P, Chambrin H, Iron A, Couzigou P, Cassaigne A
Abstract excerpt
In this study the GSTmu phenotype and ADH genotype at the ADH3 locus were investigated in a group of 39 alcoholic men with upper respiratory/digestive tract cancer: 21 with oropharyngeal cancer and 18 with laryngeal cancer. The results are compared with those of a control group of 37 alcoholic men without alcohol-related medical complications. Of the control subjects, 48% were found to be GSTmu deficient...
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