Article
Alcohol dehydrogenase 3 and risk of squamous cell carcinomas of the head and neck.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2005
Wang Donghong, Ritchie Justine M, Smith Elaine M, Zhang Zugui, Turek Lubomir P, Haugen Thomas H
Abstract excerpt
In order to examine the association between alcohol dehydrogenase 3 (ADH3) genotypes and risk of head and neck squamous cell carcinomas (HNSCC), we conducted a hospital based case-control study including 348 cases and 330 controls. DNA isolated from exfoliated cells from the oral cavity were genotyped for ADH3 polymorphisms using PCR followed by SspI digestion. Odds ratios (OR) and hazards ratios (HR) were done...
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