Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers.

Journal of the National Cancer Institute - 19 Nov 1997

Harty L C, Caporaso N E, Hayes R B, Winn D M, Bravo-Otero E, Blot W J, Kleinman D V, Brown L M, Armenian H K, Fraumeni J F, Shields P G

Abstract excerpt

BACKGROUND: The consumption of alcoholic beverages is a strong risk factor for cancers of the oral cavity and pharynx (oral cancers). Alcohol dehydrogenase type 3 (ADH3) metabolizes ethanol to acetaldehyde, a carcinogen. We evaluated whether individuals homozygous for the fast-metabolizing ADH3(1) allele (ADH3[1-1]) have a greater risk of developing oral cancer in the presence of alcoholic beverage consumption...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alcohol Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcohol Drinking

Share to Case-Control Studies

Share to DNA Primers

Share to Genotype

Share to Logistic Models

Source

Identifiers

PMID: 9390539
DOI: 10.1093/jnci/89.22.1698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers.PMID 9390539Read ↗

Oral squamous cell cancer risk in relation to alcohol consumption and alcohol dehydrogenase-3 genotypes.Semantic proximity Read ↗

Alcohol dehydrogenase 3 genotype is not associated with risk of squamous cell carcinoma of the oral cavity and pharynx.Semantic proximity Read ↗

Alcohol dehydrogenase 3 and risk of squamous cell carcinomas of the head and neck.Semantic proximity Read ↗

Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype.Semantic proximity Read ↗

Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer risk.Semantic proximity Read ↗

Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract.Semantic proximity Read ↗

ADH3 genotype, alcohol intake and breast cancer risk.Semantic proximity Read ↗

Impact of alcohol dehydrogenase 3 (ADH3 or ADH1C) genetic variation on head and neck cancer susceptibility: A systematic review, meta-analysis, functional analysis, and trial sequential analysis.Semantic proximity Read ↗

Oral cancer and polymorphism of ethanol metabolising genes.Semantic proximity Read ↗

Polymorphisms in alcohol metabolizing genes and the risk of head and neck cancer in a Brazilian population.Semantic proximity Read ↗

Interaction between a single nucleotide polymorphism in the alcohol dehydrogenase 3 gene, alcohol consumption and oral cancer risk.Semantic proximity Read ↗

Alcohol dehydrogenase 3 and risk of esophageal and gastric adenocarcinomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.