Article
Classification of chemical allergens according to cytokine secretion profiles of murine lymph node cells.
Journal of applied toxicology : JAT - 1 Jan 2000
Dearman R J, Smith S, Basketter D A, Kimber I
Abstract excerpt
Characteristic cytokine secretion profiles, consistent with the selective activation of discrete functional subpopulations of T helper (Th) cells, have been demonstrated following repeated topical exposure of mice to chemical contact or respiratory allergens. Draining lymph node cells (LNC) derived from animals treated with the respiratory allergen trimellitic anhydride (TMA; 10%) expressed high levels of the Th2...
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