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Article

The popliteal lymph node assay in mice: screening of drugs and other chemicals for immunotoxic hazard.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Dec 1996

Goebel C, Griem P, Sachs B, Bloksma N, Gleichmann E

Abstract excerpt

The popliteal lymph node assay (PLNA) in mice represents a predictive test for assessing the sensitizing (allergenic and autoimmunogenic) potential of drugs and low molecular weight chemicals. Measuring activation of the draining lymph node of the hind paw, the PLNA facilitates the detection and analysis of immunotoxic effects in a rapid and reproducible manner. An attractive feature of the PLNA is that it can be...

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PMID: 8988408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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