Article
Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation.
Toxicology in vitro : an international journal published in association with BIBRA - 1 Dec 2008
Dearman Rebecca J, Cumberbatch Marie, Portsmouth Craig, Maxwell Gavin, Basketter David A, Kimber Ian
Abstract excerpt
There is considerable interest in the development of in vitro methods for the identification of contact sensitizers, including those that use cultured dendritic cells (DC), key players in cutaneous immune responses. Chemical allergens, such as dinitrobenzene sulfonic acid (DNBS), or skin irritant...
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