Article
Phenotypic analysis of lymphocyte subpopulations in lymph nodes draining the ear following exposure to contact allergens and irritants.
Fundamental and applied toxicology : official journal of the Society of Toxicology - 1 Nov 1996
Sikorski E E, Gerberick G F, Ryan C A, Miller C M, Ridder G M
Abstract excerpt
The murine local lymph node assay (LLNA) measures in vivo proliferation in draining lymph nodes (DLN) following topical exposure to chemicals to assess contact sensitization potential. However, proliferation has also been observed with some irritants. To further characterize events in the DLN dur...
Topics
- Allergens
- Animals
- Ear
- Female
- Irritants
- Lymph Nodes
- Lymphocyte Subsets
- Mice
- Mice, Inbred BALB C
- Mice, Inbred CBA
- Phenotype
