Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic analysis of lymphocyte subpopulations in lymph nodes draining the ear following exposure to contact allergens and irritants.

Fundamental and applied toxicology : official journal of the Society of Toxicology - 1 Nov 1996

Sikorski E E, Gerberick G F, Ryan C A, Miller C M, Ridder G M

Abstract excerpt

The murine local lymph node assay (LLNA) measures in vivo proliferation in draining lymph nodes (DLN) following topical exposure to chemicals to assess contact sensitization potential. However, proliferation has also been observed with some irritants. To further characterize events in the DLN during the LLNA and distinguish allergens from irritants, phenotypic analysis of lymphocyte subsets was made following...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergens
Share to Ear

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymph Nodes

Share to Lymphocyte Subsets

Share to Mice, Inbred BALB C

Share to Mice, Inbred CBA

Share to Phenotype

Source

Identifiers

PMID: 8937889
DOI: 10.1006/faat.1996.0172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic analysis of lymphocyte subpopulations in lymph nodes draining the ear following exposure to contact allergens and irritants.PMID 8937889Read ↗

Local lymph node assay: differentiating allergic and irritant responses using flow cytometry.Semantic proximity Read ↗

Development of a flow cytometry assay for the identification and differentiation of chemicals with the potential to elicit irritation, IgE-mediated, or T cell-mediated hypersensitivity responses.Semantic proximity Read ↗

Cytometric profile of molybdenum-induced contact sensitization versus a strong allergen reaction to oxazolone in murine auricular lymph node (ALN) test.Semantic proximity Read ↗

The popliteal lymph node assay in mice: screening of drugs and other chemicals for immunotoxic hazard.Semantic proximity Read ↗

A modification of the local lymph node assay for contact allergenicity screening: measurement of interleukin-2 as an alternative to radioisotope-dependent proliferation assay.Semantic proximity Read ↗

Classification of chemical allergens according to cytokine secretion profiles of murine lymph node cells.Semantic proximity Read ↗

Sensitising potential of four textile dyes and some of their metabolites in a modified local lymph node assay.Semantic proximity Read ↗

Anchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing dataSemantic proximity Read ↗

A Role for Regulatory T Cells in a Murine Model of Epicutaneous Toluene Diisocyanate Sensitization.Semantic proximity Read ↗

Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate.Semantic proximity Read ↗

Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations.Semantic proximity Read ↗

Innate and adaptive immune responses in allergic contact dermatitis and autoimmune skin diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.