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Article

Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Mar 2005

Matheson Joanna M, Johnson Victor J, Vallyathan Velayudhan, Luster Michael I

Abstract excerpt

Isocyanate-induced asthma, the most commonly reported cause of occupational asthma, has been difficult to diagnose and control, in part, because the biological mechanisms responsible for the disease and the determinants of exposure have been difficult to define. Appropriate animals models of isocyanate asthma will be instrumental to further our understanding of this disease. Previous studies have demonstrated...

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PMID: 15590891
DOI: 10.1093/toxsci/kfi050

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