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Article

Allergen-induced cytokine phenotypes in mice: role of CD4 and CD8 T cell populations.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 2005

Dearman R J, Humphreys N, Skinner R A, Kimber I

Abstract excerpt

BACKGROUND: CD4+ T cells expressing type 2 cytokines have been implicated in the pathogenesis of asthma to high-molecular-weight allergens. Topical exposure of BALB/c strain mice to low-molecular-weight chemical contact and respiratory allergens stimulates type 1 and type 2 cytokine secretion phenotypes, respectively. OBJECTIVE: To examine the relative frequencies of cytokine-positive CD4+ and CD8+ T cells and...

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Source

Identifiers

PMID: 15836760
DOI: 10.1111/j.1365-2222.2005.02209.x

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