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Article

Local lymph node assay: differentiating allergic and irritant responses using flow cytometry.

Methods (San Diego, Calif.) - 1 Sept 1999

Gerberick G F, Cruse L W, Ryan C A

Abstract excerpt

The murine local lymph node assay (LLNA) is a method for assessing the contact sensitization potential of chemicals. Based on events that occur during the induction phase of a contact sensitization response, the LLNA measures the in vivo proliferation of cells in the draining lymph nodes (DLNs) of mice following topical exposure to chemicals. In terms of predictive identification of important skin sensitizers,...

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Identifiers

PMID: 10525437
DOI: 10.1006/meth.1999.0826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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