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Article

Relative susceptibilities of XPA knockout mice and their heterozygous and wild-type littermates to UVB-induced skin cancer.

Cancer research - 15 Feb 1997

Berg R J, de Vries A, van Steeg H, de Gruijl F R

Abstract excerpt

Although xeroderma pigmentosum (XP) patients are rare, carriers of XP genes (heterozygotes) are much more common. Whether such carriers have an increased skin cancer risk is unknown. Recently developed mouse models for XP have opened up the possibility of determining the skin cancer risk of heter...

Topics

Animals
Carcinoma, Squamous Cell
Disease Susceptibility
Genotype
Mice
Mice, Hairless
Mice, Knockout
Neoplasms, Radiation-Induced
Papilloma
Precancerous Conditions
Radiation Dosage
Skin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Skin Neoplasms

Xeroderma Pigmentosum

Source

Identifiers

PMID: 9044829

Genes

XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9044829-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Relative susceptibilities of XPA knockout mice and their heterozygous and wild-type littermates to UVB-induced skin cancer.PMID 9044829Read ↗

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