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Article

p53 mutations as a marker of skin cancer risk: comparison of UVA and UVB effects.

Experimental dermatology - 1 Jan 2002

de Gruijl Frank R

Abstract excerpt

The epidermis is excellently adapted to the sun's ultraviolet (UV) radiation. The p53 protein plays a crucial role in the orchestration of a cell's response to UV-induced damage, and more specifically to DNA damage. This response appears to differ between differentiated (suprabasal) and undifferentiated (basal) epidermal cells. The latter are the most likely targets in UV carcinogenesis. The UVB-related mutations...

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Source

Identifiers

PMID: 12444958
DOI: 10.1034/j.1600-0625.11.s.1.9.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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