Article
Hypotension in transgenic mice overexpressing human bradykinin B2 receptor.
Hypertension (Dallas, Tex. : 1979) - 1 Jan 1997
Wang D Z, Chao L, Chao J
Abstract excerpt
Bradykinin binds to its receptor at target organs and exerts a wide spectrum of biological activities including vasodilation, smooth muscle contraction and relaxation, pain, and inflammation. To gain a better insight into the physiological function of this potent vasoactive peptide, we created transgenic mice that harbor the human bradykinin B2 receptor transgene under the control of the Rous sarcoma virus 3'-LTR...
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