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Article

Polymorphisms in P21CIP1/WAF1 are not correlated with TP53 status in sporadic ovarian tumours.

European journal of cancer (Oxford, England : 1990) - 1 Dec 1996

Milner B J, Hosking L, Sun S, Haites N E, Foulkes W D

Abstract excerpt

In breast cancers and sarcomas, a variant polymorphism in the cell cycle inhibitor P21CIP1/WAF1 is under-represented in those individuals whose tumours contain mutated TP53. The aim of this study was to determine whether this variant polymorphism was also under-represented in those with ovarian carcinoma and TP53 mutations. We studied lymphocyte DNA from 104 women with ovarian carcinoma, 15 with borderline...

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Source

Identifiers

PMID: 9038623
DOI: 10.1016/s0959-8049(96)00306-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Polymorphisms in P21CIP1/WAF1 are not correlated with TP53 status in sporadic ovarian tumours.PMID 9038623Read ↗

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Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines.Semantic proximity Read ↗

WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.Semantic proximity Read ↗

The mutational profile of sporadic epithelial ovarian carcinoma.Semantic proximity Read ↗

A protective role for common p21WAF1/Cip1 polymorphisms in human ovarian cancer.Semantic proximity Read ↗

P53 mutation does not affect prognosis in ovarian epithelial malignancies.Semantic proximity Read ↗

Mutations and polymorphisms of the p21B transcript in breast cancer.Semantic proximity Read ↗

Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer.Semantic proximity Read ↗

p53 and WAF1 polymorphisms in Jewish-Israeli women with epithelial ovarian cancer and its association with BRCA mutations.Semantic proximity Read ↗

Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.Semantic proximity Read ↗

Molecular analysis of the Cip1/Waf1 (p21) gene in diverse types of human tumors.Semantic proximity Read ↗

Waf-1 (p21) and p53 polymorphisms in breast cancer.Semantic proximity Read ↗

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