Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A protective role for common p21WAF1/Cip1 polymorphisms in human ovarian cancer.

International journal of oncology - 1 Jul 1999

Milner B J, Brown I, Gabra H, Kitchener H C, Parkin D E, Haites N E

Abstract excerpt

The objective of this study was to compare the frequency of two common p21WAF1/Cip1 gene polymorphisms in ovarian cancer patients with that in age-matched controls, from a population originating from Eastern Scotland. Both polymorphisms were found significantly less frequently in both the constitutive and tumour tissue DNA of ovarian cancer patients (3/65; 4.6%), than in that from geographically and age-matched...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to Chromosomes, Human, Pair 6
Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclins

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

Share to Polymorphism, Single-Stranded Conformational

Share to Scotland

Source

Identifiers

PMID: 10375603
DOI: 10.3892/ijo.15.1.117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A protective role for common p21WAF1/Cip1 polymorphisms in human ovarian cancer.PMID 10375603Read ↗

Association between human cancer and two polymorphisms occurring together in the p21Waf1/Cip1 cyclin-dependent kinase inhibitor geneSemantic proximity Read ↗

Novel polymorphism in p21waf1/cip1 cyclin dependent kinase inhibitor gene: association with human esophageal cancerSemantic proximity Read ↗

Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer.Semantic proximity Read ↗

p21WAF1 mutations and human malignancies.Semantic proximity Read ↗

Polymorphisms in P21CIP1/WAF1 are not correlated with TP53 status in sporadic ovarian tumours.Semantic proximity Read ↗

Clinical and pathological associations with p53 tumour-suppressor gene mutations and expression of p21WAF1/Cip1 in colorectal carcinoma.Semantic proximity Read ↗

Aberrant promoter hypermethylation of p21 (WAF1/CIP1) gene and its impact on expression and role of polymorphism in the risk of breast cancer.Semantic proximity Read ↗

p21WAF1/CIP1 expression in colorectal carcinoma correlates with advanced disease stage and p53 mutations.Semantic proximity Read ↗

Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer.Semantic proximity Read ↗

Molecular analysis of the Cip1/Waf1 (p21) gene in diverse types of human tumors.Semantic proximity Read ↗

WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.Semantic proximity Read ↗

Analysis of p21WAF1/CIP1 in primary bladder tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.