Article
p53 and WAF1 polymorphisms in Jewish-Israeli women with epithelial ovarian cancer and its association with BRCA mutations.
BJOG : an international journal of obstetrics and gynaecology - 1 Jul 2000
Yair D, Ben Baruch G, Chetrit A, Friedman T, Hirsh Yechezkel G, Gotlieb W H, Fishman A, Beller U, Bar-Am A, Friedman E
Abstract excerpt
OBJECTIVE: To investigate whether polymorphic p53 and WAF1 alleles are associated with clinical, demographic and histopathological features and BRCA mutation in women with ovarian cancer. DESIGN: A cross-sectional study. POPULATION: Two hundred and twenty-one nonselected Israeli women with epithelial ovarian cancer. METHODS: DNA was analysed for known polymorphisms in intron 3 (a 16 nucleotide single repeat) and...
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