Article
Histamine H2 receptor gene variants: lack of association with schizophrenia.
Molecular psychiatry - 1 Mar 2000
Ito C, Morisset S, Krebs M O, Olié J P, Lôo H, Poirier M F, Lannfelt L, Schwartz J C, Arrang J M
Abstract excerpt
A role of histaminergic neuronal systems in schizophrenia was suggested by an association with several polymorphisms located in the coding region of the histamine H2-receptor (H2R) gene (Orange et al, Mol Psychiatry 1996; 1: 466-469). Using either the reference method of direct sequencing or restriction endonuclease digestion of PCR products amplified from DNA, we could not confirm the existence of these...
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