Properties of IRT-14 (TEM-45), a newly characterized mutant of TEM-type beta-lactamases.

doi:10.1128/AAC.41.2.374

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Article

Properties of IRT-14 (TEM-45), a newly characterized mutant of TEM-type beta-lactamases.

Antimicrobial agents and chemotherapy - 1 Feb 1997

Caniça M M, Barthélémy M, Gilly L, Labia R, Krishnamoorthy R, Paul G

Abstract excerpt

IRT-14 (TEM-45) is a new mutant TEM-type beta-lactamase that was isolated from clinical Escherichia coli P37 and that confers resistance to broad-spectrum penicillins with reduced sensitivity to beta-lactamase inhibitors. The MICs of amoxicillin alone and of amoxicillin combined with 2 micrograms...

Topics

Anti-Bacterial Agents
Drug Resistance, Microbial
Drug Resistance, Multiple
Escherichia coli
Isoelectric Focusing
Kinetics
Molecular Sequence Data
Mutation
Substrate Specificity
beta-Lactamases

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