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Article

Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Jan 1997

O'Toole E T, Mastronarde D N, Giddings T H, Winey M, Burke D J, McIntosh J R

Abstract excerpt

The three-dimensional organization of mitotic microtubules in a mutant strain of Saccharomyces cerevisiae has been studied by computer-assisted serial reconstruction. At the nonpermissive temperature, cdc20 cells arrested with a spindle length of approximately 2.5 microns. These spindles contained a mean of 81 microtubules (range, 56-100) compared with 23 in wild-type spindles of comparable length. This increase...

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Source

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Identifiers

PMID: 9017591
DOI: 10.1091/mbc.8.1.1
PMCID: PMC276055

Genes

CDC20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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